Good design is making something intelligible and memorable. Great design is making something memorable and meaningful.
Agriculture as we know it needs to disappear. We can design better and healthier proteins than we get from nature.
Sustainability can't be like some sort of a moral sacrifice or political dilemma or a philanthropical cause. It has to be a design challenge.
Everyone wants an iPhone, but it would be impossible to design an iPhone in China because it's not a product; it's an understanding of human nature.
Design must be functional, and functionality must be translated into visual aesthetics without any reliance on gimmicks that have to be explained.
If you don't design your own life plan, chances are you'll fall into someone else's plan. And guess what they have planned for you? Not much.
As an architect, you design for the present, with an awareness of the past, for a future which is essentially unknown.