Successful design is not the achievement of perfection but the minimization and accommodation of imperfection.
Almost all quality improvement comes via simplification of design, manufacturing... layout, processes, and procedures.
A designer knows he has achieved perfection not when there is nothing left to add, but when there is nothing left to take away.
Eventually everything connects - people, ideas, objects. The quality of the connections is the key to quality per se.
A common mistake that people make when trying to design something completely foolproof is to underestimate the ingenuity of complete fools.
The curious task of economics is to demonstrate to men how little they really know about what they imagine they can design.
The universe we observe has precisely the properties we should expect if there is, at bottom, no design, no purpose, no evil, no good, nothing but blind, pitiless indifference.
Good design is making something intelligible and memorable. Great design is making something memorable and meaningful.
I have an all-Japanese design team, and none of them speak English. So it's often funny and surprising how my ideas end up lost in translation.